Research

At CTVS we are dedicated to providing access to the most advanced, state-of-the-art surgical care for our patients and participating in the scientific advancement of surgical medicine with a commitment to excellence in medical care. We participate in clinical research studies that will provide access to the most advanced technologies and treatments for our patients. Below is a list of the studies that we are currently conducting at CTVS.

If you have any questions regarding research at CTVS, please contact the CTVS Research Department at CTVSResearch@ctvstexas.com.

Vascular Research Trials

  • Sponsor: Silk Road Medical
  • Principal Investigator: Dr. Foteh
  • Coordinator: Gina Briones, CCRC
  • Description: The ROADSTER2 Registry is intended to evaluate real world usage of the ENROUTE Transcarotid Stent when used with the ENROUTE Transcarotid Neuroprotection System by physicians of varying experience with the transcarotid technique.
  • For more information, go to: https://clinicaltrials.gov/ct2/show/NCT02536378?term=ROADSTER2&rank=1
  • Sponsor: Proteon Therapeutics
  • Principal Investigator: Dr. Settle
  • Coordinator: Donna Johnson, CCRC
  • Description: This research study is designed to assess the safety and effectiveness of an experimental drug called vonapanitase (PRT-201) in patients who have chronic kidney disease and who are undergoing surgery to create a new access point to their bloodstream for hemodialysis. Vonapanitase is a protein that has been shown in previous research studies to help keep vessels patent when applied to the outside surface of the blood vessels (arteries and veins) in patients who undergo surgery to create an arteriovenous fistula (AVF). The purpose of this study is to determine whether vonapanitase when applied to a limited segment of your blood vessel (about 2 inches) immediately after surgery is safe and improves the patency of your AVF.
  • For more information, go to: https://clinicaltrials.gov/ct2/show/NCT02414841?term=proteon&rank=2
  • Sponsor: Proteon Therapeutics, Inc.
  • Principal Investigator: Dr. Foteh
  • Coordinator: Gina Briones, CCRC
  • Description: This research study is designed to assess the safety of an experimental drug called Vonapanitase in patients who have symptomatic peripheral artery disease and who are scheduled to undergo an angioplasty of one or more arteries in the lower leg.
  • Length of Follow-up: Up to 7 months
  • Sponsor: Bard Peripheral Vascular, Inc.
  • Principal Investigator: Dr. Foteh
  • Coordinator: Isaiah Knight, CCRC
  • Description: The purpose of this study is to assess the clinical use of the UltraScore balloon to treat a blockage, or stenosis in legs.
  • Length of Follow-up: Up to 12 months

 

Cardiac Research Trials

  • Sponsor: Medtronic
  • Principal Investigator: Dr. Kerendi
  • Coordinator: Donna Johnson, CCRC
  • Description: Evaluate the safety and efficacy of Medtronic Intrepid™ TMVR System in patients with severe symptomatic mitral regurgitation who are candidates for conventional mitral valve surgery.
  • Length of Follow-up: 5 years
  • For more information, go to:  https://clinicaltrials.gov/ct2/show/NCT03242642?term=APOLLO+TMVR&rank=1.
  • Sponsor: St. Jude Medical
  • Principal Investigator: Dr. Kerendi
  • Coordinator: Samantha Messmer
  • Description: The PORTICO clinical trial is a prospective, multi-center, randomized, controlled clinical study, designed to evaluate the safety and effectiveness of the SJM Portico Transcatheter Heart Valve and Delivery Systems (Portico) via transfemoral and alternative delivery methods.
  • For more information, go to: https://clinicaltrials.gov/ct2/show/NCT02088554?term=perigon&rank=1
  • Sponsor: Edwards Lifesciences
  • Principal Investigator: Dr. Kerendi
  • Coordinator: Samantha Messmer
  • Description: To establish the safety and effectiveness of the Edwards  SAPIEN 3 Transcatheter Heart Valve in patients with severe, calcific aortic stenosis who are at low operative risk for standard aortic valve replacement (AVR).
  • For more information, go to: https://clinicaltrials.gov/ct2/show/NCT02675114?term=partner+3+edwards&rank=2

 

Thoracic Research Trials

  • Sponsor: University of Texas Southwestern Medical Center
  • CTVS Investigator: Dr. Fortes
  • Description: Pre-randomized study to determine if stereotactic ablative radiation (SAbR) improves survival over sublobar resection (SR) in high risk operable Stage I NSCLC
  • For more information, go to: https://clinicaltrials.gov/ct2/show/NCT02468024?term=stable-mates&rank=1

  • Sponsor: National Cancer Institute (NCI)
  • CTVS Investigator: Dr. Fortes
  • Description: This research trial studies genetic testing in screening patients with stage IB-IIIA non-small cell lung cancer that has been or will be removed by surgery. Studying the genes in a patient’s tumor cells may help doctors select the best treatment for patients that have certain genetic changes.
  • For more information, go to: https://clinicaltrials.gov/ct2/show/NCT02194738?term=alchemist&rank=1

  

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